Antithyroid Drug Treatment in Graves’ Disease

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Antithyroid Drug Therapy for Graves' Disease and Implications for Recurrence

Graves' disease (GD) is the most common cause of hyperthyroidism worldwide. Current therapeutic options for GD include antithyroid drugs (ATD), radioactive iodine, and thyroidectomy. ATD treatment is generally well accepted by patients and clinicians due to some advantages including normalizing thyroid function in a short time, hardly causing hypothyroidism, and ameliorating immune disorder whi...

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The thyroid function of Graves' disease patients is aggravated by depressive personality during antithyroid drug treatment

BACKGROUND We previously reported that depressive personality (the scores of hypochondriasis, depression and psychasthenia determined by the Minnesota Multiphasic Personality Inventory (MMPI)) and daily hassles of Graves' disease (GD) patients treated long trem with antithyroid drug (ATD) were significantly higher in a relapsed group than in a remitted group, even in the euthyroid state. The pr...

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Graves' disease in childhood: advances in management with antithyroid drug therapy.

Graves' disease is the most common cause of hyperthyroidism in children. Antithyroid drug (ATD) treatment is recommended as the initial treatment, leading to a marked improvement in most symptoms within 1 month of treatment initiation. Remission is achieved in 30% of children after a first course of ATD. Alternative treatments, such as radioactive iodine or thyroidectomy, are considered in case...

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A second course of antithyroid drug therapy for recurrent Graves' disease: an experience in endocrine practice

OBJECTIVE There are scarce reports regarding the prognosis of a second course of antithyroid drug (ATD) therapy on recurrent Graves' disease (GD). The aim of this study was to assess the long-term remission rate after a second ATD therapy and verify significant clinical predictors of a remission. DESIGN A prospective randomized clinical trial with long-term follow-up was conducted to evaluate...

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Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves' disease?

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ژورنال

عنوان ژورنال: Endocrinology and Metabolism

سال: 2021

ISSN: 2093-596X,2093-5978

DOI: 10.3803/enm.2021.1070